The era of personalized approach in cholesterol-lowering treatment begins. A new era in cholesterol treatment: Personalized approaches are at the forefront
Recently, heart attack cases at a young age in our country have brought high cholesterol and treatment methods back to the agenda. Altınbaş University Faculty of Medicine Cardiology Department Head Prof. Dr. Özlem Esen emphasized the importance of a personalized approach in cholesterol treatment.
KELLE PAÇA DOES NOT INCREASE CHOLESTEROL BY 1500 PERCENT
The Role and Dangers of Cholesterol
Prof. Dr. Esen stated that cholesterol is a vital building block for the body, but high levels pave the way for arteriosclerosis and cardiovascular diseases. He stated that high LDL (bad cholesterol) levels particularly increase the risk of heart attack, stroke and sudden death.
“Cholesterol-lowering drugs reduce the rate of events related to arteriosclerosis, namely heart attack, stroke and death, by 25%. The effectiveness of these treatments has been scientifically proven,” said Prof. Dr. Esen, explaining personalized treatment approaches.
Situation in Turkey and Familial High Cholesterol
Prof. Dr. Esen, who said that high cholesterol is often combined with inactivity and obesity in Turkey, stated that familial hypercholesterolemia is more common. “The risk of heart attack in individuals with this condition is approximately 20 times higher than in healthy individuals,” said Esen, emphasizing that early diagnosis is vital in cases where LDL levels are high. He stated that individuals living in high-risk countries like Turkey should be more careful than those living in low-risk countries.
Risk is Different in Every Country
Stating that it is no longer necessary to take blood samples on an empty stomach in cholesterol assessment, Prof. Dr. Özlem Esen drew attention to the importance of individual and social risk maps in treatment. Esen said, “Only patients with very high triglyceride values need to have their blood samples taken on an empty stomach.” In addition, emphasizing the importance of everyone having their Lipoprotein a (Lpa) levels measured at least once in their lives, Esen stated that with recent developments, targeted cholesterol values and medication doses are determined according to individual risks. Esen stated that differences between countries have gained importance at this point and gave examples: “Social heart disease risk maps specific to countries are decisive in treatment. For example, while Belgium, Denmark and France are among low-risk countries, Turkey, Hungary, Poland and Croatia are considered high-risk countries. The risk levels of two male individuals of the same age with the same cholesterol and blood pressure values differ in Denmark and Turkey. In addition, individuals who have had a heart attack, diabetes or kidney disease are included in the very high-risk group.”
New Treatment Era and Psychosocial Factors
Stating that the era in which the same treatment was applied to everyone is now over, Esen stated that even the social isolation and psychosocial stress conditions of individuals should be taken into consideration in treatment planning. Drawing attention to the fact that an important concept that makes cholesterol values risky is the social life of the individual, Prof. Dr. Esen shared the following information:
“The extent to which a person is socially isolated or whether they are under psychosocial stress are among the factors that affect cholesterol risk, but are difficult to quantify. These situations can be determined through detailed interviews. In addition, the presence of comorbid psychiatric diseases, migraines or disorders affecting the immune system should definitely be taken into consideration. Just as each individual’s fingerprint is different, their cardiovascular risk and cholesterol are also different.”
Common Misconceptions About Cholesterol
Prof. Dr. Esen also touched upon the common misconceptions about cholesterol and summarized them in 7 items:
- We only get cholesterol from what we eat.
The liver produces most of the cholesterol. Diet contributes only 15-20% of the total cholesterol level.
- High Cholesterol Levels Are Only Seen in the Elderly
High cholesterol can be seen in all age groups. Genetic factors and lifestyle can also cause problems at a young age.
- If Cholesterol Levels Increase, Medication Should Be Used Immediately
Medication may be necessary, but healthy eating, exercise, and stress management are often the first steps.
- People with Cholesterol Problems Should Not Eat Eggs
Egg yolk contains cholesterol but is not harmful when consumed in moderation. The important thing is the overall balance of the diet.
- Vegetable Oils Are Cholesterol-Free and Completely Safe
Vegetable oils may contain trans fats. Especially sunflower oil and coconut oil, although natural, may pose a risk to heart health.
- If Cholesterol Is Lowered, The Risk of Heart Disease Will Be Eliminated
Lowering cholesterol levels reduces the risk, but other factors such as smoking, high blood pressure and genetic factors should also be considered.
- Cholesterol Measurement Should Only Be Done On An Empty Stomach
With modern methods, fasting is not required for measuring total cholesterol and LDL. This is only necessary for individuals with high triglyceride levels.
Benefits of Cholesterol Lowering Medications
Prof. Dr. Esen, who describes the use of cholesterol-lowering drugs as a “safety belt against heart attacks,” stated that these drugs reduce the risk of heart attacks, protect against strokes and increase quality of life. Esen, who said, “Health is a whole,” stated that drug treatment should be supported by healthy nutrition and regular exercise, emphasizing the importance of treating everyone according to their individual characteristics.
Side Effects and Things to Consider
Esen, who drew attention to the fact that cholesterol-lowering drugs, like all drugs, can have side effects, said, “Muscle pain, increased liver enzymes and, rarely, increased blood sugar are known side effects of these drugs. Therefore, the use of cholesterol-lowering drugs should be under the supervision of a doctor and requires regular follow-up. Of course, the most correct approach would be for a doctor to examine and evaluate the patient in all aspects.”
Source: HORECA TREND and Science and Health News Agency